And the Croatian left his side a man light after just 10 minutes when French referee Clement Turpin showed no leniency for another late challenge on Lacazette.
Moments later, Simeone was also dismissed by the officious referee for taking his protests too far when an Arsenal player wasn’t booked for what he thought was a similar foul.
Griezmann grabs equaliser
Atletico’s excellent defensive record is what has carried them to five European semi-finals in seven seasons under Simeone.
The visitors battened down the hatches with 10 men, but were reliant on Oblak to keep them in the tie.
— Atlético de Madrid (@atletienglish) April 26, 2018
Wilshere headed straight at Oblak when unmarked at the back post at the end of a flowing Arsenal move.
And the Slovenian then spread himself well with an outstretched leg to deny Danny Welbeck.
Atletico retreated ever deeper towards their own goal after the break and were finally punished on the hour mark when Wilshere’s deep cross found Lacazette rising above Lucas Hernandez to head in his seventh goal in seven games.
However, the French international and Arsenal could have had more.
Laczette’s dangerous ball across goal found no takers before he headed another good opportunity wide.
And Arsenal paid heavily for their profligacy, and some comical defending, when Atletico grabbed a vital away goal on 82 minutes.
Griezmann outmuscled French international team-mate Laurent Koscielny and then benefited from a slip by Shkodran Mustafi after his initial effort had been saved by David Ospina to prod his 27th goal of the season into the roof of the net.
There was still time for Oblak to show why Griezmann isn’t the only Atletico player wanted by Europe’s elite with a spectacular one-handed save to turn Aaron Ramsey’s header behind and keep Los Rojiblancos on course for another European final
It ends level at the Emirates…
Reaching the final is going to be tough – but we CAN do it! Let’s stick together and do the job in Madrid ? pic.twitter.com/U6SRdb7Ozu
— Arsenal FC (@Arsenal) April 26, 2018