A cholera epidemic has left 857 people dead since the start of the year, the World Health Organization said last month.
Impoverished and battle-weary residents of the Beni region have said they hope the polls will bring some stability and a respite from inter-ethnic violence.
A shadowy armed group rooted in Ugandan Islam, the Allied Democratic Forces (ADF) militia based in the mineral-rich east, has killed hundreds of people since 2014.
In the past month, 48 deaths in Beni have been attributed to the ADF, including seven UN peacekeepers who were killed in an operation against the group, according to an AFP toll.
The violence has cast a shadow over efforts to roll back the Ebola outbreak and could also hamper the organisation of the election, the UN has said.
On Friday, the UN rights chief denounced opposition-targeted violence by security forces and called for “essential conditions for credible elections” to be fully protected.